Naringin dihydrochalcone, also known as naringin dihydrochalcone, is an organic compound:
1. Basic information
Molecular formula: C27H34O14 (also C28H36O15 in some sources, which may be due to minor differences in different sources or preparation methods)
Molecular weight: 582.55 (also shown as 612.58 in some sources)
CAS No.: 18916-17-1
Melting point: different sources report different melting points, generally between 131~158°C
Boiling point: 916.8ºC at 760 mmHg
Density: 1.63g/cm3 (predicted value)
Solubility: Soluble in hot water and dimethyl sulfoxide
2. Source and Preparation
Naringin dihydrochalcone is a flavonoid derivative obtained from naringin extracted from natural citrus plants and hydrogenated. The preparation process may involve multi-step chemical reactions, including base treatment, hydrogenation, ion exchange, recrystallization and other steps. The specific preparation method may vary depending on the patent and process.
3. Pharmacological effects and applications
Sweetener: naringenin dihydrochalcone, as a new type of sweetener, is 500-700 times sweeter than sucrose. It has the characteristics of high sweetness, low calorific value, non-toxicity, safety, etc. It is especially suitable for dairy products, fats and oils, frozen foods, processed vegetables, jellies, jams, non-alcoholic beverages, chewing gum, toothpaste and oral tablets and other food, medicine and daily chemical industry.
Shield bitter taste: naringenin dihydrochalcone has excellent bitter taste shielding effect, can effectively reduce the body’s sensitivity to beverages or pharmaceuticals may have a bitter taste.
Physiological activity: Research experiments show that naringenin dihydrochalcone has strong antioxidant properties, can reduce blood sugar and blood lipids, inhibit fatty liver, regulate immunity and other important physiological activities. It can also significantly scavenge stable free radicals and reactive oxygen species (ROS), and has an inhibitory effect on protein degradation and DNA strand breaks, with potential for treating reactive oxygen species-induced related diseases.